TABLE OF CONTENTS
- The Overall Objective of The R & I Project Nutrigen 4.0 is to design a Biotechnological Process, which can monitor, simulate and predict outcomes so nutraceuticals can be created by means of advanced calculation and modelling tools.
- The results obtained from the pilot initiative Will make it positive to implement new, more efficient production process, opening up the possibility of creating personalized formulas for consumers thanks to the study of the genomic profiles of the fungal strains included.
- The Project is part of the "AID FOR STRATEGIC R & D&I PROJECTS ALIGNED WITH INDUSTRY 4.0" so named by the gallician innovation agency (gain) of the "Intelixent and sosible factory" Program.
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Hifas da Terra (HDT) and the ANFACO-CECOPESCA Technological Center present The Industrial Innovation Project Nutrigen 4.0, in which 4.0 Technologies Will Be implemented in the intelligent and substantable production of nutraceuticals made from Medicinal Mushrooms. In Addition, It Will Improve The Efficient of Production Processions and the Traceability of Raw Materials of Natural Origin, Opening Up The Possibility of Customming Certain Formulas To Specific Needs Based On The Genomic Profile of The Spa Spies Analyse.
The Virtual Presentation Event "Nutrigen 4.0: Intelligent nutraceutical production Process Based on the Analysis of New Biosynthetic routes of Edible Fungi from Galicia" was Broadcast from the Central Facasies of Hdt in Bora (Pontevedra) and Included the Participation of The Scientific Director (CSO) of HDT, Dr. Arturo Rodríguez, Director of Research and Innovation (Crio) of HDT, Dr. Esteban Sinde Stompel AND, REPRESENTING THE TECHNOLOGY CENTER ANFACO-CECOPESCA, STIs Secretary General, Mr. Juan Manuel Vieites Baptista de Sousa, and the Heads of Digitalisation and Industry 4.0 and Biotechnology and Health, Hugo Barreiro and Celina Costas, respectively. The director of the Galician Innovation Agency (Gain), Patricia Argerey Vilar, spoke at the presentation ceremony, highlighting the importance of the project that "Strategic Commitment." In This Sense, She Acknowledge that "Key to addressing the challenges posed" and "Will Provide The Necessary Knowledge to Build The Industrial Future of Galicia".
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The Use of 4.0 Technologies Lands in the Food and Healthcare sector thanks to This New Nutrigen 4.0 Project. Dr. Esteban Sonde, HighLight How This "Will Allow The Development of Intelligent and Environmentally Friendly Industry, Helping Galicia To Become to European Benchmark in Healthy Eating".
Mr. Juan Manuel Vieites Baptista de Sousa, Added That This Project and ITS PARTICULAR COMMITMENT TO INDUSTRY 4.0 IN THE AGRI-FOOD AND BIOTECHNOLOGY SECTORS IS "Alledned with International Trends" and "Sets The Standard for a New Innovative Production Model" for Galicia "Facilitating Access to Globalized Markets by Achieving Excellence".
CHANGE IN THE NEXT 31 months
This initiative, as dr Arturo Rodríguez Explained, is a "PROJECT TRANSFORMATIONAL" For HDT That Will Allow The Optimization of Production Process and The DEVELOPMENT OF NEW NUTACEUTICALS BASED ON SPECIFIC FUNGAL FRACTIONS OF EXTRACTS WITH SPECIFIC HEALTH BENEFITS.
Nutrigen 4.0 is based on the Results of Previous R & D Projects in which "We Discovered That We Were Missing The Potential of the Fungal Strains Because We Did Not Know All The Details of The Production Processions". Thanks to the experience gained by the Fungitechnco Project, HDT Discovered The Potential of Mycelial Cultivation. The Cosmetinnova Project Led To Improvements In The Extraction Process, The Concentration of Bioactive Compounds and An Increase in Solubility of Fungal Extracts, All of Which Affects The Bioavailability of these Compounds.
Fractionation
"Technology and Processions determine the witness of bioactive compounds", Said Dr Rodríguez. Thus, Nutrigen 4.0 Makes It Possible to Approach Fractionation "A Step Further in the Extracting Process". This System Makes It Possible to Divide Molecular Structures into Fractions to “Identify Bioactive Compounds, Just As The Pharmaceutical Industry Does”.
According to Dr Arturo Rodríguez, The Optimization of the Production Process Will Allow For More In-Deth Use of Control Sensors and Real-Time Monitoring, As Well As Communication With Warehouse Control Software, Automated Management of Production Orders and Automated Quality Analysis Protocols.
To This End, Anfaco-Cecopesca’s Experience Will Be Fundamental for Both The Monitoring of Processions and the Application of Technologies Alled with Industry Industry 4.0, As Well As for The Study of the Molecular and Cellular Mechanisms Involved in the Production of Bioactive Compounds. The Technology Center has a solid track record in that areas of Research, Backed by Multiple Projects and Recognition from The Administrations.
THE INTEGRAL CHANGES EXPECTED FROM THIS PROJECT WHILL BEED OUT IN THE CENTRAL FACILITIES OF HDT IN BORA "High Tech Rooms". Eleven the process is validated the production system Will Be Scaled Up.
Safety and Efficacy
According to Dr. Esteban Sonde, The R & D & I Work Out for More than 20 Years Has Allowed HDT TO EVOLVE FROM TRADITIONAL PRODUCTION TO CULTURE IN BIOREACTORS AND THE DEVELOPMENT OF NUTRACEUTICALS FROM HIGH QUALITY PRODUCTS DERIED FROM FUNGI.
While The Project Will Provide exhaustive control of Critical Paramers of Production, Concentration and Stabilization, It Will Also Serve To Study The Production of Fungal Secondary Metabolites With Medicinal Activity By Studying The Fungal Genome Using Big Data Bioinformatics Analysis.
Bio Technologies
Celina Costas, Head of Biotechnology and Health at Anfaco-Cecopesca, Specified The Biotechnologies That Will Be I implemented in the nutraceutical production process at hdt to analyze the Immunomodulatory and Antimicrobial Activity OF TWO OF THE FUNGAL STRAINS THAT HDT WORKS WITH. Genomics and Big Data Will Serve to “Differentiate Metabolic Pathways” While Laboratory Technologies “Will Determine The Production of Certain Metabolites, Their Concentration and the Selection of the Fractions of the Extracts With The Greatest Effect”.
This Project Will CONCLUDE WITH TO CLINICAL TRIAL In Patients in Collaboration with a National Research Center. The Results obtained Will Also Be Analysed Using 4.0 Technologies.
Personalized formulas
Thus, in This Pilot Study, The Mathematical Analysis of the Various Production, Concentration and Purification Techniques of Fungal Active Ingredients Will Allow For A Step forward in the Development of New Formulas and for the Improvement of Current Formulas Based on Their Naturally Occurring Compounds and Potential Applications.
Project details
- Hifas da Terra and ANFACO-CECOPESCA make up the consortium created for the development of the nutrigen 4.0 project, which Will have a Total Budget of € 2,058,312.86 of which HDT Will Receive € 1,004,953.01 (49%) and ANFACO-CECOPESCA € 1,013,444.83 (51%).
- This is one of the nine initiatives selected in the current Intelixent factory Program Organized by The Galician Innovation Agency Aimed AT Improving The Competitiveness of The Strategic Sectors of the Galician Economy.
Hifas da Terra is a Biotechnology Company Specialised in Nutraceuticals made from Certified Medical Organic Mushrooms.
R&D PROJECTS